| | East Palestine, OH | Youngstown, OH | United States |
| Population | 4,739 | 61,274 | 329,725,481 |
| Female Population | 51.9% | 50.0% | 50.5% |
| Male Population | 48.2% | 50.1% | 49.5% |
| Median Age | 39.8 | 38.7 | 38.4 |
| space3 | | | |
| Population - 2010 | 4,717 | 66,809 | 309,327,143 |
| Population - 2000 | 4,917 | 82,026 | 285,036,114 |
| Population - 1990 | 5,168 | 95,732 | 251,960,433 |
| Pop. 2000 to Now | -10.9% | -22.2% | 15.6% |
| Pop. 1990 to Now | -15.2% | -33.3% | 30.8% |
| space4 | | | |
| Population Density | 1,503.5 | 1,805.8 | 93.4 |
| Land Area | 3.2 | 33.9 | 3,531,905.4 |
| Water Area | 0.0 | 0.6 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | East Palestine, OH | Youngstown, OH | United States |
| Age 0 to 4 | 9.4% | 6.1% | 5.9% |
| Age 5 to 9 | 9.0% | 5.7% | 6.1% |
| Age 10 to 14 | 3.7% | 5.8% | 6.6% |
| Age 15 to 17 | 5.4% | 4.2% | 3.9% |
| Age 18 to 20 | 1.2% | 5.4% | 4.0% |
| Age 21 to 24 | 2.5% | 6.1% | 5.2% |
| Age 25 to 34 | 12.4% | 12.6% | 13.8% |
| Age 35 to 44 | 12.3% | 11.6% | 12.9% |
| Age 45 to 54 | 9.2% | 11.4% | 12.6% |
| Age 55 to 59 | 6.6% | 6.2% | 6.7% |
| Age 60 to 64 | 7.4% | 7.4% | 6.3% |
| Age 65 to 74 | 9.2% | 10.2% | 9.6% |
| Age 75 to 84 | 6.3% | 4.6% | 4.5% |
| Age 85 and over | 5.4% | 2.7% | 1.9% |
| space1 | | | |
| Race | | | |
| | East Palestine, OH | Youngstown, OH | United States |
| White | 89.0% | 41.0% | 59.4% |
| Black | 0.5% | 41.2% | 12.2% |
| Asian | 0.0% | 0.7% | 5.6% |
| Native American | 0.1% | 0.2% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.2% | 0.3% | 0.4% |
| Two or More Races | 1.2% | 5.3% | 3.2% |
| Hispanic | 9.0% | 11.4% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | East Palestine, OH | Youngstown, OH | United States |
| Married Population | 43.5% | 27.9% | 49.8% |
| Currently Married | 43.5% | 25.5% | 48.0% |
| Married but Separated | 0.0% | 2.4% | 1.8% |
| Single Population | 56.5% | 72.1% | 50.2% |
| Never Married | 26.6% | 49.8% | 33.8% |
| Divorced | 15.9% | 14.5% | 10.8% |
| Widowed | 14.0% | 7.8% | 5.6% |
| space5 | | | |
| Household Size | 2.42 | 2.19 | 2.60 |
| Households | 1,929 | 25,954 | 124,010,992 |
| Family Households | 1,208 | 13,296 | 80,755,759 |
| Married couple, w/children | 27.3% | 13.0% | 30.5% |
| Married couple, no children | 37.9% | 29.8% | 42.9% |
| Non Family Households | 721 | 12,658 | 43,255,233 |
| Single householder, w/children | 20.6% | 38.9% | 15.8% |
| Single householder, no children | 14.2% | 18.3% | 10.8% |