| | Missouri City, TX | Santa Ana, CA | United States |
| Population | 73,682 | 313,818 | 329,725,481 |
| Female Population | 53.0% | 48.6% | 50.5% |
| Male Population | 47.0% | 51.4% | 49.5% |
| Median Age | 40.7 | 33 | 38.4 |
| space3 | | | |
| Population - 2010 | 67,020 | 325,069 | 309,327,143 |
| Population - 2000 | 52,913 | 337,977 | 285,036,114 |
| Population - 1990 | 36,176 | 293,742 | 251,960,433 |
| Pop. 2000 to Now | 44.9% | -2.0% | 15.6% |
| Pop. 1990 to Now | 111.9% | 12.8% | 30.8% |
| space4 | | | |
| Population Density | 2,537.8 | 11,469.5 | 93.4 |
| Land Area | 29.0 | 27.4 | 3,531,905.4 |
| Water Area | 1.4 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Missouri City, TX | Santa Ana, CA | United States |
| Age 0 to 4 | 6.3% | 6.4% | 5.9% |
| Age 5 to 9 | 5.6% | 6.5% | 6.1% |
| Age 10 to 14 | 6.5% | 7.6% | 6.6% |
| Age 15 to 17 | 4.1% | 4.4% | 3.9% |
| Age 18 to 20 | 2.6% | 4.6% | 4.0% |
| Age 21 to 24 | 5.2% | 6.4% | 5.2% |
| Age 25 to 34 | 12.5% | 16.7% | 13.8% |
| Age 35 to 44 | 12.5% | 14.1% | 12.9% |
| Age 45 to 54 | 13.4% | 12.8% | 12.6% |
| Age 55 to 59 | 7.5% | 5.9% | 6.7% |
| Age 60 to 64 | 8.5% | 4.5% | 6.3% |
| Age 65 to 74 | 10.0% | 6.1% | 9.6% |
| Age 75 to 84 | 4.2% | 2.4% | 4.5% |
| Age 85 and over | 1.1% | 1.4% | 1.9% |
| space1 | | | |
| Race | | | |
| | Missouri City, TX | Santa Ana, CA | United States |
| White | 20.9% | 9.5% | 59.4% |
| Black | 40.3% | 0.9% | 12.2% |
| Asian | 18.7% | 11.8% | 5.6% |
| Native American | 0.0% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.2% | 0.2% |
| Other | 0.4% | 0.1% | 0.4% |
| Two or More Races | 2.3% | 0.8% | 3.2% |
| Hispanic | 17.4% | 76.7% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Missouri City, TX | Santa Ana, CA | United States |
| Married Population | 55.3% | 45.8% | 49.8% |
| Currently Married | 53.9% | 43.8% | 48.0% |
| Married but Separated | 1.4% | 2.0% | 1.8% |
| Single Population | 44.7% | 54.2% | 50.2% |
| Never Married | 29.3% | 42.7% | 33.8% |
| Divorced | 9.8% | 7.5% | 10.8% |
| Widowed | 5.6% | 3.9% | 5.6% |
| space5 | | | |
| Household Size | 2.90 | 4.04 | 2.60 |
| Households | 25,235 | 76,624 | 124,010,992 |
| Family Households | 20,179 | 61,790 | 80,755,759 |
| Married couple, w/children | 30.6% | 37.9% | 30.5% |
| Married couple, no children | 43.1% | 30.2% | 42.9% |
| Non Family Households | 5,056 | 14,834 | 43,255,233 |
| Single householder, w/children | 13.1% | 17.2% | 15.8% |
| Single householder, no children | 13.2% | 14.6% | 10.8% |