| | Upland, CA | Santee, CA | United States |
| Population | 78,624 | 59,679 | 329,725,481 |
| Female Population | 51.7% | 51.4% | 50.5% |
| Male Population | 48.3% | 48.6% | 49.5% |
| Median Age | 37.7 | 39.3 | 38.4 |
| space3 | | | |
| Population - 2010 | 73,865 | 53,677 | 309,327,143 |
| Population - 2000 | 68,393 | 52,975 | 285,036,114 |
| Population - 1990 | 63,374 | 52,902 | 251,960,433 |
| Pop. 2000 to Now | 13.8% | 9.1% | 15.6% |
| Pop. 1990 to Now | 22.8% | 9.2% | 30.8% |
| space4 | | | |
| Population Density | 5,036.5 | 3,608.4 | 93.4 |
| Land Area | 15.6 | 16.5 | 3,531,905.4 |
| Water Area | 0.0 | 0.2 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Upland, CA | Santee, CA | United States |
| Age 0 to 4 | 5.9% | 6.8% | 5.9% |
| Age 5 to 9 | 5.6% | 6.2% | 6.1% |
| Age 10 to 14 | 6.4% | 5.9% | 6.6% |
| Age 15 to 17 | 3.6% | 4.0% | 3.9% |
| Age 18 to 20 | 3.6% | 3.4% | 4.0% |
| Age 21 to 24 | 5.7% | 4.0% | 5.2% |
| Age 25 to 34 | 16.1% | 13.9% | 13.8% |
| Age 35 to 44 | 11.7% | 14.1% | 12.9% |
| Age 45 to 54 | 13.9% | 12.6% | 12.6% |
| Age 55 to 59 | 5.9% | 6.5% | 6.7% |
| Age 60 to 64 | 6.9% | 7.1% | 6.3% |
| Age 65 to 74 | 8.3% | 9.0% | 9.6% |
| Age 75 to 84 | 4.4% | 4.6% | 4.5% |
| Age 85 and over | 1.9% | 1.9% | 1.9% |
| space1 | | | |
| Race | | | |
| | Upland, CA | Santee, CA | United States |
| White | 35.4% | 67.2% | 59.4% |
| Black | 5.5% | 1.3% | 12.2% |
| Asian | 9.5% | 4.9% | 5.6% |
| Native American | 0.2% | 0.4% | 0.6% |
| Hawaiian, Pacific Islander | 0.1% | 0.1% | 0.2% |
| Other | 0.5% | 0.1% | 0.4% |
| Two or More Races | 4.2% | 5.8% | 3.2% |
| Hispanic | 44.8% | 20.2% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Upland, CA | Santee, CA | United States |
| Married Population | 48.9% | 52.2% | 49.8% |
| Currently Married | 46.9% | 50.8% | 48.0% |
| Married but Separated | 2.0% | 1.5% | 1.8% |
| Single Population | 51.1% | 47.8% | 50.2% |
| Never Married | 36.3% | 30.2% | 33.8% |
| Divorced | 9.8% | 12.8% | 10.8% |
| Widowed | 4.9% | 4.8% | 5.6% |
| space5 | | | |
| Household Size | 2.85 | 2.81 | 2.60 |
| Households | 27,386 | 20,620 | 124,010,992 |
| Family Households | 19,787 | 14,804 | 80,755,759 |
| Married couple, w/children | 29.0% | 35.7% | 30.5% |
| Married couple, no children | 42.2% | 39.4% | 42.9% |
| Non Family Households | 7,599 | 5,816 | 43,255,233 |
| Single householder, w/children | 15.3% | 11.8% | 15.8% |
| Single householder, no children | 13.4% | 13.1% | 10.8% |