| | Frederick, MD | Bethesda, MD | United States |
| Population | 76,376 | 66,294 | 329,725,481 |
| Female Population | 51.0% | 51.9% | 50.5% |
| Male Population | 49.0% | 48.1% | 49.5% |
| Median Age | 36.9 | 43 | 38.4 |
| space3 | | | |
| Population - 2010 | 65,508 | 58,537 | 309,327,143 |
| Population - 2000 | 52,767 | 55,277 | 285,036,114 |
| Population - 1990 | 40,148 | 62,936 | 251,960,433 |
| Pop. 2000 to Now | 38.9% | 16.3% | 15.6% |
| Pop. 1990 to Now | 82.6% | 2.2% | 30.8% |
| space4 | | | |
| Population Density | 3,297.3 | 4,998.8 | 93.4 |
| Land Area | 23.2 | 13.3 | 3,531,905.4 |
| Water Area | 0.2 | 0.1 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Frederick, MD | Bethesda, MD | United States |
| Age 0 to 4 | 5.9% | 5.3% | 5.9% |
| Age 5 to 9 | 5.8% | 6.9% | 6.1% |
| Age 10 to 14 | 6.7% | 7.0% | 6.6% |
| Age 15 to 17 | 3.7% | 4.1% | 3.9% |
| Age 18 to 20 | 3.6% | 2.3% | 4.0% |
| Age 21 to 24 | 5.5% | 4.1% | 5.2% |
| Age 25 to 34 | 15.7% | 10.4% | 13.8% |
| Age 35 to 44 | 14.3% | 12.3% | 12.9% |
| Age 45 to 54 | 13.1% | 15.5% | 12.6% |
| Age 55 to 59 | 6.9% | 7.2% | 6.7% |
| Age 60 to 64 | 5.0% | 6.2% | 6.3% |
| Age 65 to 74 | 8.0% | 10.9% | 9.6% |
| Age 75 to 84 | 3.9% | 4.9% | 4.5% |
| Age 85 and over | 1.8% | 2.9% | 1.9% |
| space1 | | | |
| Race | | | |
| | Frederick, MD | Bethesda, MD | United States |
| White | 54.9% | 70.1% | 59.4% |
| Black | 17.1% | 4.7% | 12.2% |
| Asian | 5.1% | 11.3% | 5.6% |
| Native American | 0.2% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.2% | 0.7% | 0.4% |
| Two or More Races | 4.9% | 4.2% | 3.2% |
| Hispanic | 17.5% | 9.0% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Frederick, MD | Bethesda, MD | United States |
| Married Population | 47.9% | 60.9% | 49.8% |
| Currently Married | 45.7% | 60.2% | 48.0% |
| Married but Separated | 2.2% | 0.7% | 1.8% |
| Single Population | 52.1% | 39.1% | 50.2% |
| Never Married | 35.0% | 26.6% | 33.8% |
| Divorced | 11.7% | 8.0% | 10.8% |
| Widowed | 5.4% | 4.4% | 5.6% |
| space5 | | | |
| Household Size | 2.43 | 2.44 | 2.60 |
| Households | 30,644 | 26,930 | 124,010,992 |
| Family Households | 18,686 | 17,529 | 80,755,759 |
| Married couple, w/children | 34.7% | 42.0% | 30.5% |
| Married couple, no children | 35.7% | 45.9% | 42.9% |
| Non Family Households | 11,958 | 9,401 | 43,255,233 |
| Single householder, w/children | 18.2% | 6.5% | 15.8% |
| Single householder, no children | 11.4% | 5.6% | 10.8% |