| | Hartford, CT | Holyoke, MA | United States |
| Population | 121,562 | 38,480 | 329,725,481 |
| Female Population | 52.1% | 51.7% | 50.5% |
| Male Population | 47.9% | 48.3% | 49.5% |
| Median Age | 33 | 36.5 | 38.4 |
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| Population - 2010 | 125,349 | 39,917 | 309,327,143 |
| Population - 2000 | 121,578 | 39,838 | 285,036,114 |
| Population - 1990 | 139,739 | 43,704 | 251,960,433 |
| Pop. 2000 to Now | 0.0% | 0.2% | 15.6% |
| Pop. 1990 to Now | -13.0% | -8.7% | 30.8% |
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| Population Density | 6,994.8 | 1,818.1 | 93.4 |
| Land Area | 17.4 | 21.2 | 3,531,905.4 |
| Water Area | 0.7 | 1.6 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Hartford, CT | Holyoke, MA | United States |
| Age 0 to 4 | 5.7% | 6.4% | 5.9% |
| Age 5 to 9 | 6.7% | 5.8% | 6.1% |
| Age 10 to 14 | 7.0% | 7.0% | 6.6% |
| Age 15 to 17 | 4.0% | 4.2% | 3.9% |
| Age 18 to 20 | 7.4% | 4.0% | 4.0% |
| Age 21 to 24 | 6.6% | 5.6% | 5.2% |
| Age 25 to 34 | 15.7% | 15.3% | 13.8% |
| Age 35 to 44 | 13.2% | 11.7% | 12.9% |
| Age 45 to 54 | 11.9% | 12.4% | 12.6% |
| Age 55 to 59 | 5.3% | 5.8% | 6.7% |
| Age 60 to 64 | 5.1% | 6.1% | 6.3% |
| Age 65 to 74 | 7.2% | 8.5% | 9.6% |
| Age 75 to 84 | 2.9% | 4.2% | 4.5% |
| Age 85 and over | 1.4% | 3.2% | 1.9% |
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| Race | | | |
| | Hartford, CT | Holyoke, MA | United States |
| White | 14.7% | 42.0% | 59.4% |
| Black | 34.1% | 2.3% | 12.2% |
| Asian | 2.6% | 0.8% | 5.6% |
| Native American | 0.1% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.6% | 0.1% | 0.4% |
| Two or More Races | 2.5% | 1.5% | 3.2% |
| Hispanic | 45.5% | 53.3% | 18.4% |
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| Marriage & Family | | | |
| | Hartford, CT | Holyoke, MA | United States |
| Married Population | 27.4% | 33.9% | 49.8% |
| Currently Married | 24.9% | 31.7% | 48.0% |
| Married but Separated | 2.5% | 2.2% | 1.8% |
| Single Population | 72.6% | 66.1% | 50.2% |
| Never Married | 56.8% | 51.6% | 33.8% |
| Divorced | 11.4% | 9.6% | 10.8% |
| Widowed | 4.4% | 4.9% | 5.6% |
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| Household Size | 2.43 | 2.48 | 2.60 |
| Households | 46,879 | 15,062 | 124,010,992 |
| Family Households | 26,099 | 9,182 | 80,755,759 |
| Married couple, w/children | 20.1% | 15.4% | 30.5% |
| Married couple, no children | 19.3% | 32.1% | 42.9% |
| Non Family Households | 20,780 | 5,880 | 43,255,233 |
| Single householder, w/children | 37.6% | 33.6% | 15.8% |
| Single householder, no children | 23.1% | 18.9% | 10.8% |