| | Jefferson, IA | Duncan, OK | United States |
| Population | 4,178 | 22,664 | 329,725,481 |
| Female Population | 54.0% | 51.9% | 50.5% |
| Male Population | 46.1% | 48.1% | 49.5% |
| Median Age | 47.7 | 38.7 | 38.4 |
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| Population - 2010 | 4,355 | 23,438 | 309,327,143 |
| Population - 2000 | 4,626 | 22,505 | 285,036,114 |
| Population - 1990 | 4,292 | 21,732 | 251,960,433 |
| Pop. 2000 to Now | -11.9% | -1.1% | 15.6% |
| Pop. 1990 to Now | -5.1% | 2.4% | 30.8% |
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| Population Density | 700.1 | 528.6 | 93.4 |
| Land Area | 6.0 | 42.9 | 3,531,905.4 |
| Water Area | 0.0 | 4.9 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Jefferson, IA | Duncan, OK | United States |
| Age 0 to 4 | 5.2% | 6.8% | 5.9% |
| Age 5 to 9 | 4.3% | 6.7% | 6.1% |
| Age 10 to 14 | 7.1% | 6.5% | 6.6% |
| Age 15 to 17 | 3.8% | 3.9% | 3.9% |
| Age 18 to 20 | 2.5% | 3.9% | 4.0% |
| Age 21 to 24 | 5.2% | 4.1% | 5.2% |
| Age 25 to 34 | 8.6% | 13.5% | 13.8% |
| Age 35 to 44 | 11.4% | 11.6% | 12.9% |
| Age 45 to 54 | 8.4% | 11.5% | 12.6% |
| Age 55 to 59 | 6.3% | 6.3% | 6.7% |
| Age 60 to 64 | 8.8% | 6.6% | 6.3% |
| Age 65 to 74 | 14.3% | 11.1% | 9.6% |
| Age 75 to 84 | 8.7% | 4.9% | 4.5% |
| Age 85 and over | 5.5% | 2.7% | 1.9% |
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| Race | | | |
| | Jefferson, IA | Duncan, OK | United States |
| White | 92.8% | 75.3% | 59.4% |
| Black | 0.1% | 2.5% | 12.2% |
| Asian | 0.4% | 0.7% | 5.6% |
| Native American | 0.0% | 3.6% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.1% | 0.2% |
| Other | 0.0% | 0.3% | 0.4% |
| Two or More Races | 2.4% | 6.3% | 3.2% |
| Hispanic | 4.3% | 11.1% | 18.4% |
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| Marriage & Family | | | |
| | Jefferson, IA | Duncan, OK | United States |
| Married Population | 45.6% | 51.3% | 49.8% |
| Currently Married | 43.7% | 49.5% | 48.0% |
| Married but Separated | 1.9% | 1.9% | 1.8% |
| Single Population | 54.4% | 48.7% | 50.2% |
| Never Married | 24.1% | 25.4% | 33.8% |
| Divorced | 16.0% | 14.0% | 10.8% |
| Widowed | 14.4% | 9.2% | 5.6% |
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| Household Size | 2.07 | 2.49 | 2.60 |
| Households | 1,965 | 8,938 | 124,010,992 |
| Family Households | 995 | 5,730 | 80,755,759 |
| Married couple, w/children | 22.8% | 29.9% | 30.5% |
| Married couple, no children | 52.1% | 43.4% | 42.9% |
| Non Family Households | 970 | 3,208 | 43,255,233 |
| Single householder, w/children | 12.4% | 17.6% | 15.8% |
| Single householder, no children | 12.8% | 9.1% | 10.8% |