2025 Compare Cities Rankings:
Knoxville, TN vs Simpsonville, SC

#4 America's Migraine Hot Spots

#10 Drought-Riskiest Cities

#42 America's Best and Worst Cities for Crime (Large Metro Areas)

#47 The Most (and Least) Gender Imbalanced Cities

#73 Most Comfortable Summer Cities

#76 America's Most (and Least) Stressful Cities (100 Largest Metro Areas)

#77 Most Popular Cities for the Holidays

#81 The Most Single Cities

#103 2005 Best Places to Live

#216 Best Green Cities

#1 Worst Cities for Respiratory Infections

#9 Drought-Riskiest Cities

#9 America's Migraine Hot Spots

#41 America's Most (and Least) Stressful Cities (100 Largest Metro Areas)

#64 The Most (and Least) Gender Imbalanced Cities

#66 Most Comfortable Summer Cities

#80 2005 Best Places to Live

#90 The Most Single Cities

#90 Most Popular Cities for the Holidays

#230 Best Green Cities

What’s not to like? Friendly folks, mountains, rivers, lakes, streams, trees, amazing southern cuisine. Minimal traffic, solid museums, kid friendly everything, great  More

I lived in Knoxville for 3 years and still go there to see a doctor of mine until my treatment is over. You could not pay me to return to Knoxville now that I foster  More

This is my second residence in Knoxville and I'm loving my return after a 30 year absence. I love the city and county and the atmosphere surrounding them. What's not to  More

I've lived in this city for 30 years and I've seen so many changes! This is a great place to live! I've owned a business in town for 10 years and I feel safe. If I have  More

Nice suburb of Greenville, growing in diversity and culture. Competing healthcare providers (important!). Upscale manufacturing in the area (BMW and Michelin) results  More

Lived in Simpsonville for 9 years. Too long. It's a dirty little town with lots of crime and police. City government is mostly dependent on traffic fines and they  More