| | Live Oak, FL | Lake City, FL | United States |
| Population | 6,771 | 12,325 | 329,725,481 |
| Female Population | 49.6% | 51.6% | 50.5% |
| Male Population | 50.4% | 48.5% | 49.5% |
| Median Age | 40.3 | 35.9 | 38.4 |
| space3 | | | |
| Population - 2010 | 6,856 | 11,898 | 309,327,143 |
| Population - 2000 | 6,480 | 9,980 | 285,036,114 |
| Population - 1990 | 6,332 | 10,005 | 251,960,433 |
| Pop. 2000 to Now | 7.9% | 24.5% | 15.6% |
| Pop. 1990 to Now | 10.4% | 24.2% | 30.8% |
| space4 | | | |
| Population Density | 887.5 | 1,040.3 | 93.4 |
| Land Area | 7.6 | 11.8 | 3,531,905.4 |
| Water Area | 0.0 | 0.4 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Live Oak, FL | Lake City, FL | United States |
| Age 0 to 4 | 3.8% | 10.6% | 5.9% |
| Age 5 to 9 | 6.9% | 7.8% | 6.1% |
| Age 10 to 14 | 3.5% | 6.1% | 6.6% |
| Age 15 to 17 | 5.9% | 3.3% | 3.9% |
| Age 18 to 20 | 7.2% | 4.1% | 4.0% |
| Age 21 to 24 | 6.6% | 3.6% | 5.2% |
| Age 25 to 34 | 5.9% | 12.8% | 13.8% |
| Age 35 to 44 | 18.8% | 13.0% | 12.9% |
| Age 45 to 54 | 8.0% | 10.7% | 12.6% |
| Age 55 to 59 | 6.3% | 6.3% | 6.7% |
| Age 60 to 64 | 9.9% | 5.2% | 6.3% |
| Age 65 to 74 | 11.8% | 8.9% | 9.6% |
| Age 75 to 84 | 3.7% | 5.3% | 4.5% |
| Age 85 and over | 1.8% | 2.2% | 1.9% |
| space1 | | | |
| Race | | | |
| | Live Oak, FL | Lake City, FL | United States |
| White | 40.0% | 54.8% | 59.4% |
| Black | 42.2% | 31.9% | 12.2% |
| Asian | 0.0% | 1.4% | 5.6% |
| Native American | 0.0% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 1.7% | 0.4% |
| Two or More Races | 9.6% | 6.0% | 3.2% |
| Hispanic | 8.2% | 4.0% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Live Oak, FL | Lake City, FL | United States |
| Married Population | 31.7% | 40.6% | 49.8% |
| Currently Married | 29.3% | 38.3% | 48.0% |
| Married but Separated | 2.4% | 2.3% | 1.8% |
| Single Population | 68.3% | 59.4% | 50.2% |
| Never Married | 37.9% | 34.9% | 33.8% |
| Divorced | 20.4% | 17.8% | 10.8% |
| Widowed | 10.0% | 6.6% | 5.6% |
| space5 | | | |
| Household Size | 2.60 | 2.43 | 2.60 |
| Households | 2,452 | 4,813 | 124,010,992 |
| Family Households | 1,406 | 2,521 | 80,755,759 |
| Married couple, w/children | 10.9% | 30.1% | 30.5% |
| Married couple, no children | 42.5% | 30.3% | 42.9% |
| Non Family Households | 1,046 | 2,292 | 43,255,233 |
| Single householder, w/children | 33.1% | 24.8% | 15.8% |
| Single householder, no children | 13.5% | 14.8% | 10.8% |