| | Maquoketa, IA | Manchester, IA | United States |
| Population | 6,123 | 5,077 | 329,725,481 |
| Female Population | 50.1% | 50.7% | 50.5% |
| Male Population | 49.9% | 49.3% | 49.5% |
| Median Age | 39.8 | 49.4 | 38.4 |
| space3 | | | |
| Population - 2010 | 6,230 | 5,180 | 309,327,143 |
| Population - 2000 | 6,112 | 5,257 | 285,036,114 |
| Population - 1990 | 6,111 | 5,137 | 251,960,433 |
| Pop. 2000 to Now | -3.1% | -4.8% | 15.6% |
| Pop. 1990 to Now | -3.1% | -2.6% | 30.8% |
| space4 | | | |
| Population Density | 1,374.7 | 1,046.4 | 93.4 |
| Land Area | 4.5 | 4.9 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Maquoketa, IA | Manchester, IA | United States |
| Age 0 to 4 | 7.2% | 6.1% | 5.9% |
| Age 5 to 9 | 7.0% | 5.5% | 6.1% |
| Age 10 to 14 | 6.6% | 6.3% | 6.6% |
| Age 15 to 17 | 4.1% | 4.3% | 3.9% |
| Age 18 to 20 | 0.7% | 4.4% | 4.0% |
| Age 21 to 24 | 5.3% | 3.5% | 5.2% |
| Age 25 to 34 | 12.5% | 6.5% | 13.8% |
| Age 35 to 44 | 11.2% | 9.5% | 12.9% |
| Age 45 to 54 | 11.1% | 11.7% | 12.6% |
| Age 55 to 59 | 7.2% | 6.6% | 6.7% |
| Age 60 to 64 | 6.3% | 10.4% | 6.3% |
| Age 65 to 74 | 11.0% | 10.7% | 9.6% |
| Age 75 to 84 | 5.5% | 9.5% | 4.5% |
| Age 85 and over | 4.5% | 5.1% | 1.9% |
| space1 | | | |
| Race | | | |
| | Maquoketa, IA | Manchester, IA | United States |
| White | 91.5% | 95.6% | 59.4% |
| Black | 1.6% | 0.0% | 12.2% |
| Asian | 0.0% | 0.0% | 5.6% |
| Native American | 0.0% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 2.1% | 0.0% | 0.2% |
| Other | 0.4% | 0.0% | 0.4% |
| Two or More Races | 2.6% | 2.8% | 3.2% |
| Hispanic | 1.8% | 1.6% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Maquoketa, IA | Manchester, IA | United States |
| Married Population | 49.2% | 58.7% | 49.8% |
| Currently Married | 46.9% | 58.2% | 48.0% |
| Married but Separated | 2.2% | 0.4% | 1.8% |
| Single Population | 50.8% | 41.3% | 50.2% |
| Never Married | 28.0% | 21.4% | 33.8% |
| Divorced | 13.1% | 11.3% | 10.8% |
| Widowed | 9.8% | 8.6% | 5.6% |
| space5 | | | |
| Household Size | 2.34 | 2.30 | 2.60 |
| Households | 2,544 | 2,164 | 124,010,992 |
| Family Households | 1,580 | 1,327 | 80,755,759 |
| Married couple, w/children | 30.8% | 25.7% | 30.5% |
| Married couple, no children | 41.1% | 60.6% | 42.9% |
| Non Family Households | 964 | 837 | 43,255,233 |
| Single householder, w/children | 20.1% | 9.4% | 15.8% |
| Single householder, no children | 8.0% | 4.3% | 10.8% |