| | Mediapolis, IA | Lincoln, NE | United States |
| Population | 2,095 | 289,136 | 329,725,481 |
| Female Population | 51.0% | 49.6% | 50.5% |
| Male Population | 49.0% | 50.4% | 49.5% |
| Median Age | 35 | 33 | 38.4 |
| space3 | | | |
| Population - 2010 | 1,559 | 259,464 | 309,327,143 |
| Population - 2000 | 1,644 | 225,581 | 285,036,114 |
| Population - 1990 | 1,637 | 191,972 | 251,960,433 |
| Pop. 2000 to Now | -7.9% | 28.8% | 15.6% |
| Pop. 1990 to Now | -7.5% | 51.3% | 30.8% |
| space4 | | | |
| Population Density | 1,744.4 | 3,048.7 | 93.4 |
| Land Area | 1.2 | 94.8 | 3,531,905.4 |
| Water Area | 0.0 | 1.4 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Mediapolis, IA | Lincoln, NE | United States |
| Age 0 to 4 | 11.6% | 6.1% | 5.9% |
| Age 5 to 9 | 6.0% | 6.3% | 6.1% |
| Age 10 to 14 | 4.3% | 6.3% | 6.6% |
| Age 15 to 17 | 4.3% | 3.7% | 3.9% |
| Age 18 to 20 | 2.8% | 6.5% | 4.0% |
| Age 21 to 24 | 2.2% | 9.3% | 5.2% |
| Age 25 to 34 | 18.9% | 14.4% | 13.8% |
| Age 35 to 44 | 11.3% | 12.8% | 12.9% |
| Age 45 to 54 | 7.2% | 10.4% | 12.6% |
| Age 55 to 59 | 7.5% | 5.2% | 6.7% |
| Age 60 to 64 | 4.2% | 5.4% | 6.3% |
| Age 65 to 74 | 10.5% | 8.2% | 9.6% |
| Age 75 to 84 | 6.4% | 3.7% | 4.5% |
| Age 85 and over | 2.9% | 1.6% | 1.9% |
| space1 | | | |
| Race | | | |
| | Mediapolis, IA | Lincoln, NE | United States |
| White | 91.6% | 78.4% | 59.4% |
| Black | 1.2% | 4.0% | 12.2% |
| Asian | 0.1% | 4.5% | 5.6% |
| Native American | 0.0% | 0.4% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.1% | 0.2% |
| Other | 0.0% | 0.3% | 0.4% |
| Two or More Races | 2.8% | 4.2% | 3.2% |
| Hispanic | 4.3% | 8.1% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Mediapolis, IA | Lincoln, NE | United States |
| Married Population | 55.1% | 46.2% | 49.8% |
| Currently Married | 54.7% | 45.3% | 48.0% |
| Married but Separated | 0.4% | 0.9% | 1.8% |
| Single Population | 44.9% | 53.8% | 50.2% |
| Never Married | 21.2% | 39.7% | 33.8% |
| Divorced | 12.5% | 10.1% | 10.8% |
| Widowed | 11.2% | 4.0% | 5.6% |
| space5 | | | |
| Household Size | 2.43 | 2.37 | 2.60 |
| Households | 835 | 116,362 | 124,010,992 |
| Family Households | 557 | 67,144 | 80,755,759 |
| Married couple, w/children | 35.4% | 33.0% | 30.5% |
| Married couple, no children | 44.7% | 42.2% | 42.9% |
| Non Family Households | 278 | 49,218 | 43,255,233 |
| Single householder, w/children | 13.3% | 16.7% | 15.8% |
| Single householder, no children | 6.6% | 8.2% | 10.8% |