| | Yemassee, SC | Orangeburg, SC | United States |
| Population | 666 | 12,779 | 329,725,481 |
| Female Population | 63.5% | 51.6% | 50.5% |
| Male Population | 36.5% | 48.4% | 49.5% |
| Median Age | 36.6 | 36.1 | 38.4 |
| space3 | | | |
| Population - 2010 | 1,236 | 13,785 | 309,327,143 |
| Population - 2000 | 807 | 12,765 | 285,036,114 |
| Population - 1990 | 728 | 13,739 | 251,960,433 |
| Pop. 2000 to Now | 40.4% | -2.4% | 15.6% |
| Pop. 1990 to Now | 55.6% | -9.3% | 30.8% |
| space4 | | | |
| Population Density | 104.5 | 1,419.4 | 93.4 |
| Land Area | 6.4 | 9.0 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Yemassee, SC | Orangeburg, SC | United States |
| Age 0 to 4 | 5.7% | 4.1% | 5.9% |
| Age 5 to 9 | 4.1% | 4.6% | 6.1% |
| Age 10 to 14 | 11.4% | 6.1% | 6.6% |
| Age 15 to 17 | 3.5% | 1.6% | 3.9% |
| Age 18 to 20 | 0.5% | 12.4% | 4.0% |
| Age 21 to 24 | 5.9% | 7.3% | 5.2% |
| Age 25 to 34 | 15.6% | 12.9% | 13.8% |
| Age 35 to 44 | 11.0% | 11.2% | 12.9% |
| Age 45 to 54 | 5.9% | 10.7% | 12.6% |
| Age 55 to 59 | 9.6% | 5.4% | 6.7% |
| Age 60 to 64 | 5.4% | 6.3% | 6.3% |
| Age 65 to 74 | 12.6% | 9.4% | 9.6% |
| Age 75 to 84 | 7.8% | 4.8% | 4.5% |
| Age 85 and over | 1.2% | 3.2% | 1.9% |
| space1 | | | |
| Race | | | |
| | Yemassee, SC | Orangeburg, SC | United States |
| White | 38.9% | 26.1% | 59.4% |
| Black | 59.0% | 70.8% | 12.2% |
| Asian | 0.0% | 0.2% | 5.6% |
| Native American | 0.0% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 1.0% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 2.1% | 1.3% | 3.2% |
| Hispanic | 0.0% | 0.6% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Yemassee, SC | Orangeburg, SC | United States |
| Married Population | 30.3% | 30.7% | 49.8% |
| Currently Married | 26.7% | 26.7% | 48.0% |
| Married but Separated | 3.6% | 4.0% | 1.8% |
| Single Population | 69.7% | 69.3% | 50.2% |
| Never Married | 34.7% | 55.8% | 33.8% |
| Divorced | 21.3% | 6.6% | 10.8% |
| Widowed | 13.7% | 7.0% | 5.6% |
| space5 | | | |
| Household Size | 2.21 | 2.15 | 2.60 |
| Households | 301 | 4,831 | 124,010,992 |
| Family Households | 152 | 2,394 | 80,755,759 |
| Married couple, w/children | 7.2% | 10.4% | 30.5% |
| Married couple, no children | 37.5% | 44.5% | 42.9% |
| Non Family Households | 149 | 2,437 | 43,255,233 |
| Single householder, w/children | 38.2% | 23.2% | 15.8% |
| Single householder, no children | 17.1% | 21.9% | 10.8% |