| | Thermopolis, WY | Mesquite, NV | United States |
| Population | 2,826 | 20,019 | 329,725,481 |
| Female Population | 50.5% | 49.6% | 50.5% |
| Male Population | 49.5% | 50.4% | 49.5% |
| Median Age | 44.1 | 59.7 | 38.4 |
| space3 | | | |
| Population - 2010 | 3,014 | 15,305 | 309,327,143 |
| Population - 2000 | 3,172 | 9,389 | 285,036,114 |
| Population - 1990 | 3,247 | 1,871 | 251,960,433 |
| Pop. 2000 to Now | -12.7% | 117.7% | 15.6% |
| Pop. 1990 to Now | -14.7% | 992.4% | 30.8% |
| space4 | | | |
| Population Density | 1,183.9 | 633.9 | 93.4 |
| Land Area | 2.4 | 31.6 | 3,531,905.4 |
| Water Area | 0.1 | 0.4 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Thermopolis, WY | Mesquite, NV | United States |
| Age 0 to 4 | 5.2% | 4.1% | 5.9% |
| Age 5 to 9 | 7.3% | 4.2% | 6.1% |
| Age 10 to 14 | 4.0% | 5.0% | 6.6% |
| Age 15 to 17 | 3.5% | 2.6% | 3.9% |
| Age 18 to 20 | 3.6% | 2.1% | 4.0% |
| Age 21 to 24 | 5.2% | 2.2% | 5.2% |
| Age 25 to 34 | 9.8% | 7.4% | 13.8% |
| Age 35 to 44 | 11.9% | 8.6% | 12.9% |
| Age 45 to 54 | 9.6% | 9.4% | 12.6% |
| Age 55 to 59 | 5.8% | 5.0% | 6.7% |
| Age 60 to 64 | 6.1% | 7.4% | 6.3% |
| Age 65 to 74 | 17.8% | 24.9% | 9.6% |
| Age 75 to 84 | 6.1% | 14.0% | 4.5% |
| Age 85 and over | 4.2% | 3.1% | 1.9% |
| space1 | | | |
| Race | | | |
| | Thermopolis, WY | Mesquite, NV | United States |
| White | 91.8% | 65.2% | 59.4% |
| Black | 0.0% | 1.0% | 12.2% |
| Asian | 0.0% | 2.2% | 5.6% |
| Native American | 1.4% | 0.9% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.6% | 0.2% |
| Other | 1.7% | 0.1% | 0.4% |
| Two or More Races | 1.7% | 1.7% | 3.2% |
| Hispanic | 3.4% | 28.2% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Thermopolis, WY | Mesquite, NV | United States |
| Married Population | 51.6% | 61.1% | 49.8% |
| Currently Married | 51.0% | 59.3% | 48.0% |
| Married but Separated | 0.6% | 1.8% | 1.8% |
| Single Population | 48.4% | 38.9% | 50.2% |
| Never Married | 23.2% | 18.9% | 33.8% |
| Divorced | 16.5% | 11.0% | 10.8% |
| Widowed | 8.7% | 9.0% | 5.6% |
| space5 | | | |
| Household Size | 2.16 | 2.34 | 2.60 |
| Households | 1,279 | 8,522 | 124,010,992 |
| Family Households | 776 | 5,921 | 80,755,759 |
| Married couple, w/children | 23.5% | 14.8% | 30.5% |
| Married couple, no children | 50.9% | 68.9% | 42.9% |
| Non Family Households | 503 | 2,601 | 43,255,233 |
| Single householder, w/children | 14.9% | 8.7% | 15.8% |
| Single householder, no children | 10.7% | 7.6% | 10.8% |