| | Roseburg, OR | Florence, OR | United States |
| Population | 23,551 | 9,353 | 329,725,481 |
| Female Population | 50.3% | 57.3% | 50.5% |
| Male Population | 49.7% | 42.7% | 49.5% |
| Median Age | 40.1 | 60.4 | 38.4 |
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| Population - 2010 | 22,801 | 8,493 | 309,327,143 |
| Population - 2000 | 20,017 | 7,263 | 285,036,114 |
| Population - 1990 | 17,032 | 5,162 | 251,960,433 |
| Pop. 2000 to Now | 17.4% | 26.8% | 15.6% |
| Pop. 1990 to Now | 37.9% | 78.4% | 30.8% |
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| Population Density | 2,194.3 | 1,744.6 | 93.4 |
| Land Area | 10.7 | 5.4 | 3,531,905.4 |
| Water Area | 0.2 | 0.7 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Roseburg, OR | Florence, OR | United States |
| Age 0 to 4 | 5.4% | 2.7% | 5.9% |
| Age 5 to 9 | 5.1% | 4.1% | 6.1% |
| Age 10 to 14 | 7.2% | 3.6% | 6.6% |
| Age 15 to 17 | 3.5% | 1.9% | 3.9% |
| Age 18 to 20 | 2.5% | 3.3% | 4.0% |
| Age 21 to 24 | 4.7% | 2.7% | 5.2% |
| Age 25 to 34 | 15.2% | 9.4% | 13.8% |
| Age 35 to 44 | 11.3% | 5.6% | 12.9% |
| Age 45 to 54 | 11.0% | 9.4% | 12.6% |
| Age 55 to 59 | 6.5% | 6.4% | 6.7% |
| Age 60 to 64 | 7.6% | 8.1% | 6.3% |
| Age 65 to 74 | 9.9% | 23.4% | 9.6% |
| Age 75 to 84 | 5.3% | 14.2% | 4.5% |
| Age 85 and over | 4.8% | 5.2% | 1.9% |
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| Race | | | |
| | Roseburg, OR | Florence, OR | United States |
| White | 85.3% | 88.3% | 59.4% |
| Black | 0.2% | 1.7% | 12.2% |
| Asian | 1.1% | 1.0% | 5.6% |
| Native American | 0.7% | 0.8% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.1% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 6.6% | 2.7% | 3.2% |
| Hispanic | 6.1% | 5.4% | 18.4% |
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| Marriage & Family | | | |
| | Roseburg, OR | Florence, OR | United States |
| Married Population | 46.2% | 50.0% | 49.8% |
| Currently Married | 43.4% | 47.4% | 48.0% |
| Married but Separated | 2.8% | 2.6% | 1.8% |
| Single Population | 53.8% | 50.0% | 50.2% |
| Never Married | 31.4% | 21.4% | 33.8% |
| Divorced | 15.1% | 16.2% | 10.8% |
| Widowed | 7.2% | 12.5% | 5.6% |
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| Household Size | 2.21 | 1.97 | 2.60 |
| Households | 10,249 | 4,714 | 124,010,992 |
| Family Households | 5,787 | 2,559 | 80,755,759 |
| Married couple, w/children | 26.6% | 12.9% | 30.5% |
| Married couple, no children | 42.1% | 58.5% | 42.9% |
| Non Family Households | 4,462 | 2,155 | 43,255,233 |
| Single householder, w/children | 22.6% | 12.6% | 15.8% |
| Single householder, no children | 8.7% | 16.0% | 10.8% |