| | Sister Bay, WI | Manitowoc, WI | United States |
| Population | 960 | 34,267 | 329,725,481 |
| Female Population | 57.3% | 50.2% | 50.5% |
| Male Population | 42.7% | 49.9% | 49.5% |
| Median Age | 58.6 | 43.4 | 38.4 |
| space3 | | | |
| Population - 2010 | 877 | 33,646 | 309,327,143 |
| Population - 2000 | 886 | 34,053 | 285,036,114 |
| Population - 1990 | 675 | 32,520 | 251,960,433 |
| Pop. 2000 to Now | 5.4% | -5.0% | 15.6% |
| Pop. 1990 to Now | 38.4% | -0.5% | 30.8% |
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| Population Density | 372.1 | 1,927.3 | 93.4 |
| Land Area | 2.6 | 17.8 | 3,531,905.4 |
| Water Area | 1.0 | 0.4 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Sister Bay, WI | Manitowoc, WI | United States |
| Age 0 to 4 | 10.5% | 5.1% | 5.9% |
| Age 5 to 9 | 6.3% | 5.1% | 6.1% |
| Age 10 to 14 | 2.6% | 6.8% | 6.6% |
| Age 15 to 17 | 0.5% | 4.0% | 3.9% |
| Age 18 to 20 | 1.0% | 3.0% | 4.0% |
| Age 21 to 24 | 1.3% | 4.6% | 5.2% |
| Age 25 to 34 | 9.4% | 12.0% | 13.8% |
| Age 35 to 44 | 11.5% | 10.9% | 12.9% |
| Age 45 to 54 | 4.1% | 12.4% | 12.6% |
| Age 55 to 59 | 4.1% | 7.6% | 6.7% |
| Age 60 to 64 | 4.9% | 7.6% | 6.3% |
| Age 65 to 74 | 19.5% | 12.2% | 9.6% |
| Age 75 to 84 | 10.3% | 5.7% | 4.5% |
| Age 85 and over | 14.2% | 3.1% | 1.9% |
| space1 | | | |
| Race | | | |
| | Sister Bay, WI | Manitowoc, WI | United States |
| White | 95.6% | 84.3% | 59.4% |
| Black | 0.0% | 2.1% | 12.2% |
| Asian | 0.0% | 5.5% | 5.6% |
| Native American | 0.0% | 0.4% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.1% | 0.4% |
| Two or More Races | 0.9% | 2.1% | 3.2% |
| Hispanic | 3.4% | 5.6% | 18.4% |
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| Marriage & Family | | | |
| | Sister Bay, WI | Manitowoc, WI | United States |
| Married Population | 56.2% | 46.4% | 49.8% |
| Currently Married | 54.7% | 45.0% | 48.0% |
| Married but Separated | 1.6% | 1.4% | 1.8% |
| Single Population | 43.8% | 53.6% | 50.2% |
| Never Married | 13.8% | 31.3% | 33.8% |
| Divorced | 14.9% | 14.1% | 10.8% |
| Widowed | 15.1% | 8.2% | 5.6% |
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| Household Size | 1.70 | 2.24 | 2.60 |
| Households | 544 | 14,874 | 124,010,992 |
| Family Households | 280 | 8,404 | 80,755,759 |
| Married couple, w/children | 6.4% | 24.8% | 30.5% |
| Married couple, no children | 67.9% | 45.4% | 42.9% |
| Non Family Households | 264 | 6,470 | 43,255,233 |
| Single householder, w/children | 23.2% | 21.0% | 15.8% |
| Single householder, no children | 2.5% | 8.8% | 10.8% |