| | West Plains, MO | Murray, KY | United States |
| Population | 12,048 | 17,241 | 329,725,481 |
| Female Population | 52.1% | 50.1% | 50.5% |
| Male Population | 47.9% | 49.9% | 49.5% |
| Median Age | 33.9 | 25.6 | 38.4 |
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| Population - 2010 | 12,053 | 17,835 | 309,327,143 |
| Population - 2000 | 10,866 | 14,950 | 285,036,114 |
| Population - 1990 | 8,913 | 14,439 | 251,960,433 |
| Pop. 2000 to Now | 14.0% | 30.0% | 15.6% |
| Pop. 1990 to Now | 38.9% | 34.6% | 30.8% |
| space4 | | | |
| Population Density | 908.1 | 1,484.9 | 93.4 |
| Land Area | 13.3 | 11.6 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | West Plains, MO | Murray, KY | United States |
| Age 0 to 4 | 8.1% | 3.7% | 5.9% |
| Age 5 to 9 | 7.0% | 3.9% | 6.1% |
| Age 10 to 14 | 5.8% | 3.8% | 6.6% |
| Age 15 to 17 | 3.6% | 2.3% | 3.9% |
| Age 18 to 20 | 4.3% | 20.2% | 4.0% |
| Age 21 to 24 | 5.0% | 15.0% | 5.2% |
| Age 25 to 34 | 17.0% | 12.5% | 13.8% |
| Age 35 to 44 | 12.1% | 8.9% | 12.9% |
| Age 45 to 54 | 10.5% | 9.2% | 12.6% |
| Age 55 to 59 | 4.6% | 4.8% | 6.7% |
| Age 60 to 64 | 5.0% | 3.6% | 6.3% |
| Age 65 to 74 | 8.3% | 6.1% | 9.6% |
| Age 75 to 84 | 4.9% | 4.4% | 4.5% |
| Age 85 and over | 3.9% | 1.7% | 1.9% |
| space1 | | | |
| Race | | | |
| | West Plains, MO | Murray, KY | United States |
| White | 95.9% | 84.5% | 59.4% |
| Black | 0.6% | 6.5% | 12.2% |
| Asian | 0.2% | 3.1% | 5.6% |
| Native American | 0.4% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.5% | 0.2% |
| Other | 0.0% | 0.4% | 0.4% |
| Two or More Races | 2.1% | 3.1% | 3.2% |
| Hispanic | 0.7% | 1.9% | 18.4% |
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| Marriage & Family | | | |
| | West Plains, MO | Murray, KY | United States |
| Married Population | 44.9% | 31.9% | 49.8% |
| Currently Married | 42.0% | 30.5% | 48.0% |
| Married but Separated | 2.9% | 1.4% | 1.8% |
| Single Population | 55.1% | 68.1% | 50.2% |
| Never Married | 31.9% | 53.9% | 33.8% |
| Divorced | 13.4% | 9.7% | 10.8% |
| Widowed | 9.8% | 4.5% | 5.6% |
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| Household Size | 2.42 | 2.15 | 2.60 |
| Households | 4,803 | 6,341 | 124,010,992 |
| Family Households | 2,573 | 3,053 | 80,755,759 |
| Married couple, w/children | 29.6% | 31.1% | 30.5% |
| Married couple, no children | 37.2% | 40.2% | 42.9% |
| Non Family Households | 2,230 | 3,288 | 43,255,233 |
| Single householder, w/children | 23.0% | 22.8% | 15.8% |
| Single householder, no children | 10.2% | 5.9% | 10.8% |