| | Zanesville, OH | Cleveland, OH | United States |
| Population | 24,809 | 374,861 | 329,725,481 |
| Female Population | 50.6% | 51.8% | 50.5% |
| Male Population | 49.4% | 48.2% | 49.5% |
| Median Age | 37 | 36.2 | 38.4 |
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| Population - 2010 | 25,462 | 396,095 | 309,327,143 |
| Population - 2000 | 25,586 | 478,403 | 285,036,114 |
| Population - 1990 | 26,778 | 505,616 | 251,960,433 |
| Pop. 2000 to Now | -1.5% | -20.9% | 15.6% |
| Pop. 1990 to Now | -5.9% | -25.1% | 30.8% |
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| Population Density | 2,108.5 | 4,824.5 | 93.4 |
| Land Area | 11.8 | 77.7 | 3,531,905.4 |
| Water Area | 0.4 | 4.8 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Zanesville, OH | Cleveland, OH | United States |
| Age 0 to 4 | 6.7% | 5.8% | 5.9% |
| Age 5 to 9 | 7.1% | 6.0% | 6.1% |
| Age 10 to 14 | 6.1% | 6.1% | 6.6% |
| Age 15 to 17 | 3.2% | 3.9% | 3.9% |
| Age 18 to 20 | 3.2% | 4.1% | 4.0% |
| Age 21 to 24 | 4.9% | 5.7% | 5.2% |
| Age 25 to 34 | 16.5% | 16.7% | 13.8% |
| Age 35 to 44 | 11.2% | 11.8% | 12.9% |
| Age 45 to 54 | 12.0% | 11.8% | 12.6% |
| Age 55 to 59 | 5.9% | 7.1% | 6.7% |
| Age 60 to 64 | 6.8% | 6.9% | 6.3% |
| Age 65 to 74 | 8.6% | 8.4% | 9.6% |
| Age 75 to 84 | 4.9% | 4.0% | 4.5% |
| Age 85 and over | 3.1% | 1.7% | 1.9% |
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| Race | | | |
| | Zanesville, OH | Cleveland, OH | United States |
| White | 81.1% | 34.0% | 59.4% |
| Black | 7.0% | 46.7% | 12.2% |
| Asian | 0.9% | 2.4% | 5.6% |
| Native American | 0.1% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.4% | 0.5% | 0.4% |
| Two or More Races | 6.8% | 4.1% | 3.2% |
| Hispanic | 3.7% | 12.2% | 18.4% |
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| Marriage & Family | | | |
| | Zanesville, OH | Cleveland, OH | United States |
| Married Population | 34.9% | 26.9% | 49.8% |
| Currently Married | 31.0% | 24.0% | 48.0% |
| Married but Separated | 3.9% | 3.0% | 1.8% |
| Single Population | 65.1% | 73.1% | 50.2% |
| Never Married | 39.6% | 53.1% | 33.8% |
| Divorced | 17.5% | 14.1% | 10.8% |
| Widowed | 8.0% | 5.9% | 5.6% |
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| Household Size | 2.33 | 2.15 | 2.60 |
| Households | 10,422 | 168,196 | 124,010,992 |
| Family Households | 5,655 | 77,098 | 80,755,759 |
| Married couple, w/children | 17.2% | 15.2% | 30.5% |
| Married couple, no children | 31.3% | 27.0% | 42.9% |
| Non Family Households | 4,767 | 91,098 | 43,255,233 |
| Single householder, w/children | 33.4% | 36.6% | 15.8% |
| Single householder, no children | 18.1% | 21.2% | 10.8% |