| | Clinton, MO | Chillicothe, MO | United States |
| Population | 8,844 | 9,253 | 329,725,481 |
| Female Population | 53.2% | 59.2% | 50.5% |
| Male Population | 46.8% | 40.8% | 49.5% |
| Median Age | 41.7 | 38.4 | 38.4 |
| space3 | | | |
| Population - 2010 | 9,002 | 9,457 | 309,327,143 |
| Population - 2000 | 9,311 | 8,968 | 285,036,114 |
| Population - 1990 | 8,703 | 8,804 | 251,960,433 |
| Pop. 2000 to Now | -2.9% | -0.6% | 15.6% |
| Pop. 1990 to Now | 3.9% | 1.3% | 30.8% |
| space4 | | | |
| Population Density | 967.0 | 1,297.2 | 93.4 |
| Land Area | 9.1 | 7.1 | 3,531,905.4 |
| Water Area | 0.1 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Clinton, MO | Chillicothe, MO | United States |
| Age 0 to 4 | 6.2% | 5.1% | 5.9% |
| Age 5 to 9 | 5.5% | 5.4% | 6.1% |
| Age 10 to 14 | 5.7% | 6.4% | 6.6% |
| Age 15 to 17 | 4.6% | 3.2% | 3.9% |
| Age 18 to 20 | 2.9% | 3.1% | 4.0% |
| Age 21 to 24 | 3.6% | 6.4% | 5.2% |
| Age 25 to 34 | 11.4% | 14.8% | 13.8% |
| Age 35 to 44 | 14.1% | 14.9% | 12.9% |
| Age 45 to 54 | 9.3% | 9.3% | 12.6% |
| Age 55 to 59 | 7.1% | 6.5% | 6.7% |
| Age 60 to 64 | 7.1% | 6.4% | 6.3% |
| Age 65 to 74 | 13.5% | 9.3% | 9.6% |
| Age 75 to 84 | 5.5% | 5.3% | 4.5% |
| Age 85 and over | 3.5% | 4.0% | 1.9% |
| space1 | | | |
| Race | | | |
| | Clinton, MO | Chillicothe, MO | United States |
| White | 91.6% | 88.3% | 59.4% |
| Black | 2.0% | 4.3% | 12.2% |
| Asian | 0.4% | 0.9% | 5.6% |
| Native American | 0.3% | 0.5% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.1% | 0.4% |
| Two or More Races | 3.7% | 3.2% | 3.2% |
| Hispanic | 2.1% | 2.6% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Clinton, MO | Chillicothe, MO | United States |
| Married Population | 41.9% | 42.6% | 49.8% |
| Currently Married | 40.2% | 40.4% | 48.0% |
| Married but Separated | 1.7% | 2.3% | 1.8% |
| Single Population | 58.1% | 57.4% | 50.2% |
| Never Married | 28.5% | 33.3% | 33.8% |
| Divorced | 19.6% | 16.4% | 10.8% |
| Widowed | 10.0% | 7.7% | 5.6% |
| space5 | | | |
| Household Size | 2.24 | 2.38 | 2.60 |
| Households | 3,858 | 3,342 | 124,010,992 |
| Family Households | 2,177 | 1,929 | 80,755,759 |
| Married couple, w/children | 21.4% | 27.4% | 30.5% |
| Married couple, no children | 38.5% | 44.0% | 42.9% |
| Non Family Households | 1,681 | 1,413 | 43,255,233 |
| Single householder, w/children | 33.2% | 21.9% | 15.8% |
| Single householder, no children | 6.9% | 6.7% | 10.8% |