| | Manning, SC | Baltimore, MD | United States |
| Population | 3,919 | 592,211 | 329,725,481 |
| Female Population | 53.8% | 52.9% | 50.5% |
| Male Population | 46.2% | 47.1% | 49.5% |
| Median Age | 44.3 | 35.7 | 38.4 |
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| Population - 2010 | 4,091 | 620,942 | 309,327,143 |
| Population - 2000 | 4,025 | 651,154 | 285,036,114 |
| Population - 1990 | 4,428 | 736,014 | 251,960,433 |
| Pop. 2000 to Now | -4.3% | -10.0% | 15.6% |
| Pop. 1990 to Now | -13.0% | -20.4% | 30.8% |
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| Population Density | 1,334.8 | 7,316.1 | 93.4 |
| Land Area | 2.9 | 80.9 | 3,531,905.4 |
| Water Area | 0.0 | 11.1 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Manning, SC | Baltimore, MD | United States |
| Age 0 to 4 | 1.3% | 6.2% | 5.9% |
| Age 5 to 9 | 6.7% | 5.5% | 6.1% |
| Age 10 to 14 | 5.6% | 5.7% | 6.6% |
| Age 15 to 17 | 5.5% | 3.1% | 3.9% |
| Age 18 to 20 | 2.5% | 4.3% | 4.0% |
| Age 21 to 24 | 5.7% | 5.1% | 5.2% |
| Age 25 to 34 | 12.8% | 18.8% | 13.8% |
| Age 35 to 44 | 11.3% | 13.0% | 12.9% |
| Age 45 to 54 | 8.7% | 11.4% | 12.6% |
| Age 55 to 59 | 4.5% | 6.4% | 6.7% |
| Age 60 to 64 | 5.0% | 6.4% | 6.3% |
| Age 65 to 74 | 15.0% | 8.7% | 9.6% |
| Age 75 to 84 | 7.9% | 3.8% | 4.5% |
| Age 85 and over | 7.6% | 1.6% | 1.9% |
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| Race | | | |
| | Manning, SC | Baltimore, MD | United States |
| White | 37.4% | 27.3% | 59.4% |
| Black | 58.6% | 60.9% | 12.2% |
| Asian | 0.3% | 2.5% | 5.6% |
| Native American | 0.0% | 0.2% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.4% | 0.4% |
| Two or More Races | 2.1% | 3.0% | 3.2% |
| Hispanic | 1.7% | 5.6% | 18.4% |
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| Marriage & Family | | | |
| | Manning, SC | Baltimore, MD | United States |
| Married Population | 33.2% | 30.3% | 49.8% |
| Currently Married | 30.9% | 27.2% | 48.0% |
| Married but Separated | 2.4% | 3.1% | 1.8% |
| Single Population | 66.8% | 69.7% | 50.2% |
| Never Married | 42.5% | 52.3% | 33.8% |
| Divorced | 11.7% | 11.4% | 10.8% |
| Widowed | 12.5% | 6.0% | 5.6% |
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| Household Size | 2.50 | 2.32 | 2.60 |
| Households | 1,544 | 244,893 | 124,010,992 |
| Family Households | 847 | 119,410 | 80,755,759 |
| Married couple, w/children | 11.8% | 18.6% | 30.5% |
| Married couple, no children | 45.2% | 30.5% | 42.9% |
| Non Family Households | 697 | 125,483 | 43,255,233 |
| Single householder, w/children | 23.1% | 29.1% | 15.8% |
| Single householder, no children | 19.8% | 21.8% | 10.8% |